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Volume-X

, Issue-II

(SPRING 2025)

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01 - Genetic Insights into Hypertension: From Candidate Gene Studies to Genome-Wide A

http://dx.doi.org/10.31703/giidr.2025(X-II).01
10.31703/giidr.2025(X-II).01      Published : Jun 2025

Abstract

    Hypertension is a multifactorial condition with both genetic and environmental causes. Although common, its genetic determinants remain unknown. Over the course of history, research has progressed from candidate gene studies often limited by small sample sizes and selection bias to large genome-wide association studies (GWAS) that have identified many common variants with minor effects. Polygenic ... Details

    Hypertension, Genome-Wide Association Studies (GWAS), Polygenic Risk Scores (PGS), Computational Genomics, Precision Medicine

    (1) Ayesha Tahir
    M.S, Institute of Microbiology and Molecular Genetics, University of the Punjab, Punjab, Pakistan.
    (2) Bisma Amjad
    M.S, Institute of Microbiology and Molecular Genetics, University of the Punjab, Punjab, Pakistan.
    (3) Sohela
    Graduate, Institute of Microbiology and Molecular Genetics, University of the Punjab, Punjab, Pakistan.
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